Drug-delivering aptamers target leukemia stem cells for one-two knockout punch

Posted 2025-04-03 22:31:53 by: Admin

Drug-carrying DNA aptamers can deliver a one-two punch to leukemia by precisely targeting the elusive cancer stem cells that seed cancer relapses, researchers at the University of Illinois Urbana-Champaign report. The aptamers - short single-strand snippets of DNA that can target molecules like larger antibodies do - not only deliver cancer-fighting drugs, but also are themselves toxic to the cancer stem cells, the researchers ...

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Successful therapy confirmed for newborns with the fatal metabolic disorder MoCD type A

Posted 2025-04-03 18:39:43 by: Admin

Early administration of the drug Fosdenopterin/rcPMP improves the chances of survival of infants with MoCD type A and promotes the development of brain ...

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MIT engineers develop a way to mass manufacture nanoparticles that deliver cancer drugs directly to tumors

Posted 2025-04-03 18:38:47 by: Admin

Researchers developed a manufacturing technique that rapidly generates large quantities of nanoparticles coated with drug-delivering polymers, which hold great potential for treating cancer. The particles can be targeted directly to tumors, where they release their payload while avoiding many of the side effects of traditional ...

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Researchers find intestinal immune cell prevents food allergies

Posted 2025-04-03 18:38:42 by: Admin

Researchers found that a small population of immune cells in the mouse intestine prevents allergic responses to food, suggesting that targeting such cells therapeutically could potentially lead to a new treatment for ...

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New vaccine concept tackles harmful bacteria in the intestine

Posted 2025-04-03 18:38:37 by: Admin

In the fight against bacterial pathogens, researchers are combining vaccination with targeted colonization of the intestine by harmless microorganisms. This approach could potentially mark a turning point in the antibiotics ...

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Cellular regulator of mRNA vaccine revealed... offering new therapeutic options

Posted 2025-04-03 18:37:37 by: Admin

A team of researchers has uncovered a key cellular mechanism that affects the function of mRNA vaccines and therapeutics. Their study provides the first comprehensive understanding of how mRNA vaccines are delivered, processed, and degraded within cells - a breakthrough that could pave the way for more effective vaccines and RNA-based ...

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Powerful new software platform could reshape biomedical research by making data analysis more accessible

Posted 2025-04-03 18:37:25 by: Admin

A powerful new software platform is set to transform biomedical research by allowing scientists to conduct complex and customized data analyses without advanced programming skills. The web-based platform enables scientists to analyze and visualize their own data independently through an intuitive, interactive ...

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Revealing capillaries and cells in living organs with ultrasound

Posted 2025-04-03 18:37:22 by: Admin

While medical centers use ultrasound daily, so far this technology has not been capable of observing body tissues at the scale of cells. Physicists have now developed a microscopy technique based on ultrasound to reveal capillaries and cells across living organs - something that wasn't possible ...

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How the brain and inner ear are formed

Posted 2025-04-03 18:37:19 by: Admin

Researchers have developed a method that shows how the nervous system and sensory organs are formed in an embryo. By labeling stem cells with a genetic 'barcode', they have been able to follow the cells' developmental journey and discover how the inner ear is formed in mice. The discovery could provide important insights for future treatment of hearing ...

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How GPS helps older drivers stay on the roads

Posted 2025-04-03 18:37:13 by: Admin

New research shows that Sat Nav systems are helping keep older drivers on the roads for longer. The study reveals that over 65s with a poorer sense of direction rely more on help from GPS navigation systems such as Sat Nav or smartphone maps. Those using GPS tended to drive more frequently - suggesting that the technology helps older people maintain driving ...

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